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MSTP Student Laboratory of Applied Mathematics takeshi.yokoo@mssm.edu Annenberg, Rm. 20-71 212.241.5470 (tel) 212.246.5037 (fax) |
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MSTP Student Laboratory of Applied Mathematics takeshi.yokoo@mssm.edu Annenberg, Rm. 20-71 212.241.5470 (tel) 212.246.5037 (fax) |
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Image Analysis, Signal Processing, Theoretical Neuroscience
Introduction |
| I am an MSTP student in the 7th year of training at Mount Sinai School of Medicine, of New York University, NY. I received Ph.D. in Biomathematical Sciences in 2004 under the guidance of Dr. Lawrence Sirovich, director of the Laboratory for Applied Mathematics , Dept. of Biomathematical Sciences. My primary research interest is mathematical / statistical image analysis, with emphasis in IOS (Intrinsic Optical Signal) imaging of the mammalian Central Nervous System. Major areas of application include mapping of the functional organization in V1 and V2 (primary and secondary visual cortices) for various types of visual information (stimulus orientation, direction of motion, spatial/temporal frequency, color and luminance contrast). I am also interested in problems of pattern-recognition, signal processing, multivariate statistics, and their applications in medical physiology, psychophysics, and biological data analysis. |
| Education
/ Experience |
| 1992-1996
1997- current 2004 2005 |
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Williams College, Williamstown, MA.
- B.A. in Mathematics, Williams College, MA. - Systems/Network Administrator, Fuji ImmunoPharmaceuticals Inc., Lexington, MA. - Medical Scientist Training Program (MSTP), Mount Sinai School of Medicine, New York, NY. - M.Phil. in Biomedical Sciences, Mount Sinai School of Medicine, NY. - Ph.D. in Biomathematical Sciences, Mount Sinai School of Medicine, NY. - M.D. (expected), Mount Sinai School of Medicine, NY. |
| Research |
I
am a member of the Laboratory for
Applied
Mathematics.VISUAL NEUROSCIENCESIGNAL AND IMAGE ANALYSISMatlabTM Function Library for Image Analysis Neuroinformatics Course at Marine Biological Laboratory, Woods Hole, MA. |
| Publications |
| PEER-REVIEWED
Yokoo, T., Knight, B.W., Sirovich, L. 2001. An Optimization Approach to Signal Extraction from Noisy Multivariate Data NeuroImage (14) 1309-1326. yokoo_2001_neuroimage.ps.gz yokoo_2001_neuroimage.pdf Sornborger, A., Yokoo, T., Delorme, A., Sailstad, C., Sirovich, L. 2003 Extraction of Average and Differential Dynamical Responses in Stimulus-locked Experimental Data. (to appear on Journal of Neuroscience Methods.) Yokoo, T., Knight, B.W., Sirovich, L. 2003. L2 De-Gaussianization and Independent Component Analysis. Proceedings of ICA 2003, 4th International Symposium on Independent Component Analysis and Blind Source Separation, Nara, Japan. Sorngorger, A. and Yokoo, T. 2004. A Multitaper Approach
to Detecting Harmonic Response in Multivariate Data. (in
preparation) Yokoo, T. 2004. Statistical Filter
Framework in Multivariate Analysis. (in preparation) ABSTRACTS Gegiu, L.M., Orchach, D., Yokoo, T., Sornborger, A., Sirovich, L., Kaplan, E. 2001 The Representation of Color in Area V1 of the Macaque Visual Cortex - An Optical Imaging Study Association of Research in Vision and Ophthalomology Meeting. Sornborger, A., Yokoo, T., Knight, B.W., Sirovich, L. 2001. Recent Advances in Image Analysis. A poster at Defence Advanced Research Project Agency (DARPA) Meeting, San Francisco, CA. Adobe PDF: darpa_poster_2001.pdf Yokoo, T., 2001. An Optimization Approach to Signal Extraction from Noisy Data. Neural Information Processing Systems workshop in Image Analysis, Whistler, BC, Canada. Sornborger, A., Roy, R. Uglesich, R., Yokoo, T., Kaplan, E., Sirovich, L. 2002. A Statistical Analysis of the Resolvability of Orientation Pinwheels in Intrinsic Optical Imaging Data. Sociery of Neuroscience Meeting, Orlando, FL. Sailstad, C.A., Yokoo, T., Sornborger, A., Sirovich, L.,
Kaplan, E.
2002. Effects of Area 18 Inactivation on Contrast Gain of
Area
17. Sociery of Neuroscience Meeting, Orlando, FL. Sornborger, A., Yokoo, T., Sailstad, C., Sirovich, L., and
Kaplan, E. 2003. Dynamics of the
Intrinsic Optical Signal: Aspects of the Global and Differential
Responses to Drifting Grating Stimuli in Cat Primary Visual Cortex.
Society of Neuroscience Meeting, New Orleans, LA. Yokoo, T., Sornborger, A., Sailstad, C., Kaplan, E., and Sirovich, L. 2003. A Mulivariate, Multitaper Approach to Signal Estimation in Bioimaging Data with Application to Optical Imaging of the Intrinsic Signal. Society of Neuroscience Meeting, New Orleans, LA. Xu, X., Gallucci, M.R., Shima, D.W., Stefansic, J.D., Thomas,
A.M., Yokoo, T., Sornborger, A., Bonds, A.B., Casagrande, V.A.
2003. Is
There Any Relationship Between Cytochrome Oxidase (CO) Blobs and
Spatial Frequency Preference Domains in Primate Visual Cortex? Society
of Neuroscience Meeting, New Orleans, LA. THESESYokoo, T. 1996. Wavelet Analysis in Dense Target Signal Processing. honors thesis, Dept. of Mathematics, Williams College, Williamstown, MA. (Advisor: Stewart Johnson)Yokoo, T. 2002. A Novel Method for Signal Analysis and its Application to Biomedical Imaging. (thesis proposal) Mount Sinai School of Medicine, New York, NY. (Advisor: Lawrence Sirovich) Download: proposal.ps.gz proposal.pdf Yokoo, T. 2004. Multivariate Statistical Analysis of Functional Neuroimaging Data. (Ph.D. thesis) Mount Sinai School of Medicine, New York, NY. (Advisor: Lawrence Sirovich) Download: thesis.pdf |